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Updated: Jun 1, 2026

Using SCOPE to Identify Potential Regulatory Motifs in Coregulated Genes
07:55

Using SCOPE to Identify Potential Regulatory Motifs in Coregulated Genes

Published on: May 31, 2011

Genome-wide identification of conserved regulatory function in diverged sequences

Leila Taher1, David M McGaughey, Samantha Maragh

  • 1Computational Biology Branch, National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA.

Genome Research
|June 2, 2011
PubMed
Summary

Scientists found that conserved transcription factor binding site (TFBS) arrangements can identify functional gene regulatory elements even with DNA sequence divergence. This reveals "covert" elements crucial for conserved gene regulation across species.

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