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CMV enteritis causing hemorrhage and obstruction in an infant with AIDS
S E Dolgin1, J G Larsen, K D Shah
1Department of Surgery, City Hospital Center, Elmhurst, New York, NY.
Journal of Pediatric Surgery
|June 1, 1990
Summary
Cytomegalovirus (CMV) enteritis caused severe gastrointestinal bleeding and fatal small bowel obstruction in an infant with acquired immunodeficiency syndrome (AIDS). This case highlights a distinct CMV enteritis presentation recognizable during surgery.
Area of Science:
- Pediatric Gastroenterology
- Infectious Diseases
- Virology
Background:
- Cytomegalovirus (CMV) infections frequently impact immunosuppressed individuals, particularly those with acquired immunodeficiency syndrome (AIDS).
- Gastrointestinal complications such as hemorrhage and perforation are common consequences of CMV infections in this population.
Observation:
- A critical case of CMV enteritis is presented in an infant diagnosed with AIDS.
- The infant experienced massive gastrointestinal hemorrhage and subsequently developed a fatal small bowel obstruction attributed to the infection.
Findings:
- Surgical examination revealed striking, diffuse yellowish plaques with central ulcerations throughout the small bowel.
- Biopsies confirmed the presence of cytomegalic inclusion bodies, indicative of CMV infection.
Implications:
- This case identifies a previously unrecognized form of CMV enteritis affecting infants.
- The distinct pathological findings are readily identifiable during laparotomy, aiding in diagnosis and management.