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A Case of Giant Bladder Carcinosarcoma without Submucosal Invasion
Masayoshi Zaitsu1, Mariko Yamanoi, Koji Mikami
1Department of Urology, Kanto Rosai Hospital, 1-1 Kizukisumiyoshi-Cho, Nakahara-ku, Kawasaki 211-8510, Japan.
Case Reports in Medicine
|June 2, 2011
Summary
This case study details a rare bladder carcinosarcoma in an elderly male. Successful transurethral resection and BCG treatment led to no recurrence at six months.
Area of Science:
- Urology
- Oncology
- Pathology
Background:
- Bladder carcinosarcoma is a rare, aggressive neoplasm with poor prognosis.
- This biphasic tumor contains both malignant epithelial and mesenchymal elements.
Observation:
- An 83-year-old male presented with painless gross hematuria and a large bladder tumor.
- Transurethral resection removed a 91g tumor diagnosed as carcinosarcoma (urothelial cancer, chondrosarcoma, leiomyosarcoma).
- Carcinoma in situ was found in surrounding mucosa post-resection.
Findings:
- Complete tumor removal via transurethral resection was achieved.
- Intravesical Bacillus Calmette-Guerin (BCG) instillation was administered weekly for six weeks.
- No tumor recurrence was observed for six months post-treatment.
Implications:
- This case highlights successful management of a rare bladder carcinosarcoma.
- Transurethral resection followed by BCG instillation may be an effective treatment strategy.
- Further research into bladder carcinosarcoma management is warranted.