Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Toxoplasmosis01:28

Toxoplasmosis

Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...
Encephalitis l: Introduction01:19

Encephalitis l: Introduction

Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...
Encephalitis ll: Pathophysiology01:26

Encephalitis ll: Pathophysiology

Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...
Arboviral Encephalitis01:25

Arboviral Encephalitis

Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
American Trypanosomiasis01:22

American Trypanosomiasis

Chagas disease, or American trypanosomiasis, is a vector-borne parasitic infection caused by Trypanosoma cruzi, a flagellated protozoan (kinetoplastid) of the family Trypanosomatidae. The disease is endemic in Latin America, although cases are increasingly reported worldwide due to human migration. Transmission most commonly occurs when feces of infected triatomine bugs contaminate bite wounds or mucosal surfaces; additional routes include congenital, transfusional, transplant-related, and oral...
Amebiasis01:28

Amebiasis

Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Neuropalliative Care in Demyelinating Diseases.

Continuum (Minneapolis, Minn.)·2025
Same author

Staging of immuno-virological dynamics during acute HIV infection in a Belgian prospective cohort study.

Journal of virus eradication·2024
Same author

Longitudinal patterns of inflammatory mediators after acute HIV infection correlate to intact and total reservoir.

Frontiers in immunology·2024
Same author

Loss of GM-CSF-dependent instruction of alveolar macrophages in COVID-19 provides a rationale for inhaled GM-CSF treatment.

Cell reports. Medicine·2022
Same author

Efficacy and safety of the investigational complement C5 inhibitor zilucoplan in patients hospitalized with COVID-19: an open-label randomized controlled trial.

Respiratory research·2022
Same author

A public health value-based healthcare paradigm for HIV.

BMC health services research·2022

Related Experiment Video

Updated: Jun 1, 2026

3-D Imaging and Analysis of Neurons Infected In Vivo with Toxoplasma gondii
06:33

3-D Imaging and Analysis of Neurons Infected In Vivo with Toxoplasma gondii

Published on: December 9, 2014

Toxocariasis presenting as encephalomyelitis.

Gregory Helsen1, Stefaan J Vandecasteele, Ludo J Vanopdenbosch

  • 1Department of Neurology, Antwerp University Hospital, Wilrijkstraat 10, 2650 Edegem, Belgium.

Case Reports in Medicine
|June 2, 2011
PubMed
Summary
This summary is machine-generated.

Neurotoxocariasis, a rare parasitic infection, can cause central nervous system inflammation. Early diagnosis and treatment with antihelminthics and corticosteroids are crucial for recovery.

More Related Videos

Modeling Multiple Sclerosis in the Two Sexes: MOG35-55-Induced Experimental Autoimmune Encephalomyelitis
05:44

Modeling Multiple Sclerosis in the Two Sexes: MOG35-55-Induced Experimental Autoimmune Encephalomyelitis

Published on: October 13, 2023

Related Experiment Videos

Last Updated: Jun 1, 2026

3-D Imaging and Analysis of Neurons Infected In Vivo with Toxoplasma gondii
06:33

3-D Imaging and Analysis of Neurons Infected In Vivo with Toxoplasma gondii

Published on: December 9, 2014

Modeling Multiple Sclerosis in the Two Sexes: MOG35-55-Induced Experimental Autoimmune Encephalomyelitis
05:44

Modeling Multiple Sclerosis in the Two Sexes: MOG35-55-Induced Experimental Autoimmune Encephalomyelitis

Published on: October 13, 2023

Area of Science:

  • Neurology
  • Infectious Diseases
  • Parasitology

Background:

  • Transverse myelitis is an inflammatory condition affecting the spinal cord.
  • Neuroparasitic infections are uncommon but can present with severe neurological deficits.

Observation:

  • A farmer presented with symptoms mimicking transverse thoracic myelitis.
  • Magnetic Resonance Imaging (MRI) revealed inflammatory lesions in the brain and thoracic spinal cord.
  • Blood and cerebrospinal fluid analysis showed eosinophilia, a key indicator of parasitic infection.

Findings:

  • The patient's condition was diagnosed as neurotoxocariasis, a rare parasitic infection caused by Toxocara worms.
  • Immunological confirmation validated the diagnosis.
  • Successful treatment involved a combination of antihelminthic medication and corticosteroids.

Implications:

  • Neurotoxocariasis diagnosis can be challenging due to diverse and atypical clinical presentations.
  • Eosinophilia in the central nervous system warrants consideration of parasitic infections like neurotoxocariasis.
  • Prompt diagnosis and combined therapy improve patient outcomes for this rare neurological syndrome.