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Imaging brain tumor by dendrimer-based optical/paramagnetic nanoprobe across the blood-brain barrier
Huihui Yan1, Jiyao Wang, Peiwei Yi
1Department of Gastroenterology, Zhongshan Hospital affiliated to Fudan University, 180 Fenglin Rd., Shanghai 200032, China.
Chemical Communications (Cambridge, England)
|June 2, 2011
Abstract:
A multimodal optical/paramagnetic nanoprobe, Den-Angio, was developed and demonstrated a capability to circumvent the blood brain barrier (BBB) and visualize brain tumors with high sensitivity in vivo. Den-Angio holds promise to pre-operatively localize brain tumors and make image-guided tumor resection possible during surgery.
