Related Experiment Video
Updated: Jun 1, 2026

Mouse Model of Acute to Chronic Kidney Disease Transition Induced by Renal Ischemia/Reperfusion Injury
Published on: February 10, 2026
Renal immaturity mimicking chronic renal failure in an infant born at 22 weeks gestational age
Ozge Aydemir1, Omer Erdeve, Serife Suna Oguz
1Department of Neonatology, Zekai Tahir Burak Maternity Teaching Hospital, Ankara, Turkey. drozgegenc@yahoo.com.tr
Abstract:
Glomerular function shows a progression directly correlated to gestational age (GA) and postnatal age in preterm infants. In preterms, glomerular filtration rate (GFR) is significantly lower than in term infants, and it matures more slowly in the postnatal period. In infants with very low GA, due to decreased GFR, normalization of serum creatinine values may be prolonged during recovery from acute renal failure (ARF). Herein, we report an extremely premature infant with high creatinine values from third week up to third month of life which normalized thereafter mimicking chronic renal failure.
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