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Updated: Jun 1, 2026

Systematic Bronchoscopy: the Four Landmarks Approach
Published on: June 23, 2023
Flexible bronchoscopy assisted by noninvasive positive pressure ventilation
Septimiu D Murgu1, Jocelyn Pecson, Henri G Colt
1Department of Medicine, University of California School of Medicine, Irvine, California, Orange, CA 92868, USA. smurgu@uci.edu
Noninvasive positive pressure ventilation (NIPPV) offers a safe alternative to intubation for critically ill patients undergoing flexible bronchoscopy. This technique may reduce complications and improve outcomes in various respiratory conditions.
Area of Science:
- Critical Care Medicine
- Pulmonology
- Respiratory Therapy
Background:
- Flexible bronchoscopy is essential for diagnosing and treating critically ill patients with respiratory failure.
- Intubation carries risks, necessitating alternative ventilatory strategies for certain procedures.
- Noninvasive positive pressure ventilation (NIPPV) has emerged as a potential adjunct to bronchoscopy.
Purpose of the Study:
- To review the physiological basis, indications, contraindications, and techniques of NIPPV-assisted flexible bronchoscopy.
- To highlight the role of critical care nurses in managing this procedure.
- To explore the benefits of NIPPV in reducing bronchoscopy-related complications.
Main Methods:
- This is a review article synthesizing existing literature on NIPPV and flexible bronchoscopy.
- The review covers physiological rationale, clinical applications, and nursing considerations.
- Data from relevant studies and clinical guidelines were analyzed.
Main Results:
- NIPPV can be a viable alternative to intubation for flexible bronchoscopy in select patients.
- It may decrease the risk of complications in patients with hypoxemia, respiratory distress, and airway collapse.
- NIPPV facilitates bronchoscopic assessment in patients with severe dyspnea.
Conclusions:
- NIPPV-assisted flexible bronchoscopy is a valuable technique for managing critically ill patients with respiratory compromise.
- Careful patient selection, technique, and monitoring are crucial for successful implementation.
- Critical care nurses play a vital role in the procedural success and patient safety.
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