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RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
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RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma

Published on: March 11, 2014

Evaluation of a new DNA test for detection of carcinogenic human papillomavirus

Philip E Castle1, Erin C Gutierrez, Sharon V Leitch

  • 1American Society for Clinical Pathology, 1225 New York Ave. NW, Suite 250, Washington, DC 20005, USA. philip.castle@ascp.org

Journal of Clinical Microbiology
|June 3, 2011
PubMed

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Mutagenicity and carcinogenicity refer to the ability of drugs to cause genetic defects and induce cancer, respectively. The International Agency for Research on Cancer (IARC) classifies agents into four groups based on their carcinogenic potential. Group 1 agents are known human carcinogens; group 2A agents are probably carcinogenic to humans; group 3 agents lack data to support their role in carcinogenesis; and group 4 includes agents for which data support that they are not likely to be...