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Updated: Jun 1, 2026

Y-90 Radioembolization and PD-1 Inhibitor as Neoadjuvant Treatment in Hepatocellular Carcinoma
Published on: May 24, 2024
Neoadjuvant sorafenib combined with gemcitabine plus oxaliplatin in advanced hepatocellular carcinoma
Nicolas Williet1, Olivier Dubreuil, Tarek Boussaha
1Department of Gastroenterology, Europeen Georges Pompidou Hospital, Medical University, 75908 Paris, France. nwilliet@yahoo.fr
Abstract:
This paper reports the first case of a patient with hepatocellular carcinoma with lymph node metastasis treated by sorafenib combined with gemcitabine plus oxaliplatin, with a partial response and normalization of α fetoprotein, which allowed curative surgery. The potential synergy between these three drugs needs to be confirmed, and is currently being investigated in a randomized phase II trial.
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