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Updated: Jun 1, 2026

A High-Throughput Image-Guided Stereotactic Neuronavigation and Focused Ultrasound System for Blood-Brain Barrier Opening in Rodents
Published on: July 16, 2020
A new system for 3D ultrasound-guided placement of cerebral ventricle catheters
I Reinertsen1, A S Jakola, P Friderichsen
1SINTEF Medical Technology, Trondheim, Norway. Ingerid.Reinertsen@sintef.no
Purpose:
We present a new system for 3D ultrasound-guided placement of cerebral ventricle catheters. The system has been developed with the aim to provide accurate ultrasound-based guidance with only minimal changes to the current surgical technique and workflow.
Methods:
The system consists of a pre-calibrated navigation adapter for the catheter and a reference frame attached to a standard surgical retractor in addition to an ultrasound-based navigation system with a probe that fits on top of a standard burr hole.
Results:
The accuracy of the pre-calibrated system has been evaluated, and our measurements indicate that the accuracy of the pre-calibrated system is better than 3 mm. We also present a clinical case.
Conclusions:
The navigation accuracy is considered sufficient for clinical use, and initial clinical tests are promising. Further testing will be necessary to fully evaluate the performance of the system in a clinical setting.

