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Updated: Jun 1, 2026

06:52
Reconstruct Human Retinoblastoma In Vitro
Published on: October 11, 2022
Complete regression of retinoblastoma following intra-arterial chemotherapy
Nina Ni1, Carol L Shields, Carlos G Bianciotto
1Ocular Oncology Service, Wills Eye Institute, 840 Walnut Street, Philadelphia, PA 19107, USA.
Journal of Pediatric Ophthalmology and Strabismus
|June 4, 2011
Abstract:
A 22-month-old girl with Group C unilateral retinoblastoma demonstrated dramatic tumor regression after two infusions of 5 mg of intra-arterial melphalan as primary therapy. Complete tumor control without recurrence was noted at 1 year. Retinal and choroidal perfusion was intact and the electroretinogram improved following therapy.
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