[Occurrence of 3 primary carcinomas within 26 months]

One case of 3 primary malignant tumors is reported. Having undergone adjuvant polychemotherapy after mastectomy for cancer of the right breast, 2 more primary malignomas were found in a 73-year-old woman within 26 months: malignant melanoma for the right upper arm and scirrhous gastric cancer. Possible induction of secondary/tertiary neoplasms by polychemotherapy with alkylating drugs is discussed. The importance of early detection of secondary/tertiary malignancies and of their delimitation against metastases is underlined as being indispensable for the proper planning of adequate therapy.