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Updated: Jun 1, 2026
09:02
Percutaneous Hepatic Perfusion (PHP) with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver
Published on: July 31, 2016
[Pathogenesis and management of refractory malignant ascites]
Esma Saâda1, Philippe Follana, Fréderic Peyrade
1Centre Antoine-Lacassagne, département d’oncologie médicale, Nice, France. saadaesma@gmail.com
Bulletin Du Cancer
|June 4, 2011
Summary
Malignant ascites, fluid accumulation in cancer patients, often indicates poor prognosis. This review explores management strategies for refractory malignant ascites, focusing on palliative care to improve patient quality of life.
Area of Science:
- Oncology
- Gastroenterology
- Palliative Care
Context:
- Malignant ascites, fluid accumulation in the peritoneal cavity, is a common complication of various adenocarcinomas, including ovarian, breast, colon, stomach, and pancreas.
- Symptoms like abdominal distention, nausea, and dyspnea significantly impact patient well-being.
- Refractory ascites, unresponsive to medical treatment, necessitates specialized palliative care.
Purpose:
- To review the pathophysiology of malignant ascites.
- To outline current and future management options for refractory malignant ascites.
- To emphasize the role of palliative care in improving the quality of life for affected patients.
Summary:
- Malignant ascites result from cancer spread to the peritoneum, lymphatic obstruction, or other systemic issues.
- Diagnosis often occurs in patients with pre-existing cancer, signaling a poor prognosis.
- Refractory malignant ascites management focuses on symptom control and quality of life within palliative care.
Impact:
- Provides a comprehensive overview of malignant ascites pathophysiology and management.
- Highlights the importance of palliative care in managing refractory malignant ascites.
- Informs clinicians on current and emerging treatment strategies for improved patient outcomes.
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