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Related Experiment Video

Updated: Jun 1, 2026

Large-area Scanning Probe Nanolithography Facilitated by Automated Alignment and Its Application to Substrate Fabrication for Cell Culture Studies
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Large-area Scanning Probe Nanolithography Facilitated by Automated Alignment and Its Application to Substrate Fabrication for Cell Culture Studies

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A nanocontact printing system for sub-100 nm aligned patterning.

Bharath R Takulapalli1, Michael E Morrison, Jian Gu

  • 1Center for Applied Nanobioscience, The Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA.

Nanotechnology
|June 4, 2011
PubMed
Summary

We developed an aligned nanocontact printing (nCP) system for sub-100 nm precision. This advanced technique utilizes moiré fringes and microfluidics for reliable nanoscale patterning, applicable to DNA nanoarrays and beyond.

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Area of Science:

  • Nanotechnology
  • Materials Science
  • Biotechnology

Background:

  • Multilayer printing in the nanometer regime faces significant challenges.
  • Existing contact printing methods require further advancements for nanoscale applications.

Purpose of the Study:

  • To develop an aligned nanocontact printing (nCP) system with sub-100 nm alignment precision.
  • To address challenges in stamp inking for nanoscale printing applications.

Main Methods:

  • Utilized moiré fringes and microspacers for achieving sub-100 nm alignment.
  • Devised a microfluidic apparatus employing gradient capillary force for ink transport.
  • Tested the nCP system by printing nucleoside phosphoramidites on a nanopillar arrayed substrate.

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Expanding Nanopatterned Substrates Using Stitch Technique for Nanotopographical Modulation of Cell Behavior

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Last Updated: Jun 1, 2026

Large-area Scanning Probe Nanolithography Facilitated by Automated Alignment and Its Application to Substrate Fabrication for Cell Culture Studies
09:45

Large-area Scanning Probe Nanolithography Facilitated by Automated Alignment and Its Application to Substrate Fabrication for Cell Culture Studies

Published on: June 12, 2018

Creating Two-Dimensional Patterned Substrates for Protein and Cell Confinement
08:36

Creating Two-Dimensional Patterned Substrates for Protein and Cell Confinement

Published on: September 6, 2011

Expanding Nanopatterned Substrates Using Stitch Technique for Nanotopographical Modulation of Cell Behavior
09:06

Expanding Nanopatterned Substrates Using Stitch Technique for Nanotopographical Modulation of Cell Behavior

Published on: December 8, 2016

Main Results:

  • Demonstrated a sub-100 nm alignment capability in the nanocontact printing system.
  • Successfully addressed stamp inking issues using a novel microfluidic ink transport method.
  • Validated the nCP system's performance through printing on a nanopillar array.

Conclusions:

  • The developed aligned nanocontact printing (nCP) system offers high precision for nanoscale patterning.
  • The microfluidic ink delivery system enhances reliability in nanoscale printing.
  • The nCP system holds potential for fabricating high-density DNA nanoarrays and other nanotechnology applications.