Related Experiment Video
Updated: Jun 1, 2026

An Ex vivo Culture System to Study Thyroid Development
Published on: June 6, 2014
A unique case of thyroid dysgenesis in a neonate
Adam Bryant1, Marion C Reid, M Elizabeth Oates
1Department of Radiology, University of Kentucky Medical Center, Lexington, KY, USA. albrya0@email.uky.edu
Abstract:
Neonates with congenital hypothyroidism often demonstrate ectopic thyroid tissue. However, 2 sites of abnormally located thyroid tissue are exceptionally rare with only one other published case on a neonate. The authors present a unique case of a neonate who was found to have congenital hypothyroidism on laboratory screening; Tc-99m pertechnetate scintigraphy demonstrated 2 sites of abnormal uptake: one at the base of the tongue and the other in the midline at the expected location of the thyroid bed.
Related Concept Videos
The Thyroid Gland
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
Hyperthyroidism I: Introduction
Synthesis and Regulation of Thyroid Hormones
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The iodine is then...
Hypothyroidism II: Pathophysiology
Goiter
Graves' Disease I: Introduction
