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Cutaneous sarcoidosis evaluated by FDG PET.
1VA Greater Los Angeles Healthcare System, Department of Nuclear Medicine, Los Angeles, CA 90073, USA.
Clinical Nuclear Medicine
|June 4, 2011
Summary
This case study highlights a rare presentation of sarcoidosis affecting the skin and lungs. Early diagnosis and treatment led to a significant reduction in disease activity, demonstrating effective therapeutic response.
Area of Science:
- Dermatology
- Pulmonology
- Nuclear Medicine
Background:
- Sarcoidosis is a multisystem inflammatory disease characterized by noncaseating granulomas.
- Cutaneous and pulmonary involvement can occur, presenting with diverse clinical manifestations.
Observation:
- A 50-year-old male presented with diffuse skin pain, pruritus, skin plaques, and subcutaneous nodules.
- Physical examination and skin biopsy confirmed noncaseating epithelioid granulomas.
- The patient subsequently developed respiratory symptoms including cough and shortness of breath.
Findings:
- Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography (FDG PET/CT) revealed widespread skin involvement.
- FDG PET/CT demonstrated a significant decrease in uptake after therapy, indicating a positive treatment response.
Implications:
- This case underscores the utility of FDG PET/CT in assessing sarcoidosis extent and treatment efficacy.
- Early recognition and management of cutaneous and pulmonary sarcoidosis are crucial for favorable outcomes.
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