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Glucosamine hydrochloride functionalized water-soluble conjugated polyfluorene: synthesis, characterization, and
Qi Chen1, Qian-Yi Cheng, Yan-Chao Zhao
1National Center for Nanoscience and Technology, Beijing 100190, China.
Abstract:
Novel glucosamine hydrochloride functionalized water-soluble conjugated polyfluorene was easily synthesized through Cu(I)-catalyzed azide/alkyne "click" ligation and Suzuki coupling polymerization. The water-solubility and biocompatibility of the polymer were improved after grafting glucosamine hydrochloride to the side chains of the conjugated polymer. As a fluorescent model system of chitosan, its interaction with single-stranded DNA was studied by spectrofluorometric titration.
