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Adenovirus type 21 keratoconjunctivitis.

S Darougar, R Pearce, J A Gibson

    The British Journal of Ophthalmology
    |December 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

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    A case of adenovirus type 21 caused severe keratoconjunctivitis in London. This viral eye infection presented with persistent conjunctivitis and punctate keratitis, mimicking other adenovirus strains.

    Area of Science:

    • Ophthalmology
    • Virology
    • Infectious Diseases

    Background:

    • Adenovirus infections can cause ocular disease, including epidemic keratoconjunctivitis.
    • Adenovirus type 8 is a common cause of epidemic keratoconjunctivitis.
    • The clinical presentation and course of adenoviral eye infections can vary by serotype.

    Observation:

    • A 59-year-old woman presented with a 3-week history of left eye redness, grittiness, watery discharge, and photophobia.
    • Clinical examination revealed moderate follicular conjunctivitis lasting 6 weeks.
    • Corneal examination showed epithelial and subepithelial punctate keratitis, with subepithelial opacities persisting for 4 months.

    Findings:

    • Conjunctival swabbing confirmed the presence of adenovirus serotype 21.

    Related Experiment Videos

  • The patient's follicular conjunctivitis and subepithelial punctate keratitis were clinically similar to epidemic keratoconjunctivitis caused by adenovirus 8.
  • This case highlights adenovirus type 21 as a cause of severe keratoconjunctivitis.

    • Implications:

    • Adenovirus type 21 should be considered in the differential diagnosis of severe keratoconjunctivitis.
    • Understanding the clinical spectrum of different adenovirus serotypes is crucial for accurate diagnosis and management.
    • This case contributes to the epidemiological data of adenoviral eye infections.