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Related Concept Videos

Protein Networks02:26

Protein Networks

An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
Protein Networks02:26

Protein Networks

An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
Protein Organization01:24

Protein Organization

Proteins are polymers of amino acid residues. They are versatile and responsible for different cellular functions, including DNA replication, molecular transport, catalysis, and structural support. Proteins have a hierarchical structure comprising at least three levels of organization: primary, secondary, and tertiary structure. Some large proteins have a quaternary structure where individual protein subunits are linked together.
The primary structure of a protein is its amino acid sequence.
Protein Organization01:13

Protein Organization

Overview
Protein Organization01:24

Protein Organization

Proteins are polymers of amino acid residues. They are versatile and responsible for different cellular functions, including DNA replication, molecular transport, catalysis, and structural support. Proteins have a hierarchical structure comprising at least three levels of organization: primary, secondary, and tertiary structure. Some large proteins have a quaternary structure where individual protein subunits are linked together.
The primary structure of a protein is its amino acid sequence.
Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...

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Related Experiment Video

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Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web
09:51

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web

Published on: July 16, 2017

Computer programming and biomolecular structure studies: A step beyond internet bioinformatics.

Vladimir A Likić1

  • 1The Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, 30 Flemington Road, Parkville 3010, Australia. vlikic@unimelb.edu.au.

Biochemistry and Molecular Biology Education : a Bimonthly Publication of the International Union of Biochemistry and Molecular Biology
|June 4, 2011
PubMed
Summary

This study introduces undergraduate students to structural bioinformatics by teaching programming skills. This approach enables practical problem-solving in biomolecular structure and bioinformatics, bypassing traditional internet-dependent methods.

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A Protocol for Computer-Based Protein Structure and Function Prediction
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A Protocol for Computer-Based Protein Structure and Function Prediction

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A Protocol for Computer-Based Protein Structure and Function Prediction
16:41

A Protocol for Computer-Based Protein Structure and Function Prediction

Published on: November 3, 2011

Area of Science:

  • Biomolecular Structure
  • Bioinformatics
  • Computational Biology

Background:

  • Traditional bioinformatics education often relies on internet-based tools and databases.
  • Undergraduate students, particularly those with biological backgrounds, may lack programming proficiency.
  • Limited time and resources pose challenges for introducing programming in a bioinformatics curriculum.

Purpose of the Study:

  • To describe the experience of teaching structural bioinformatics to undergraduate students.
  • To introduce computer programming as a practical skill for bioinformatics problem-solving.
  • To develop an alternative to internet-dependent bioinformatics approaches.

Main Methods:

  • Teaching programming fundamentals to students with a biological background.
  • Integrating programming into practical sessions focused on macromolecular structure.
  • Utilizing a problem-based learning approach relevant to structure-function relationships.

Main Results:

  • Students were successfully introduced to programming from a beginner level within a limited timeframe.
  • The programming approach provided an alternative to traditional internet bioinformatics methods.
  • Students gained the ability to independently solve a simple bioinformatics problem related to biomolecular structure.

Conclusions:

  • Teaching programming as part of a structural bioinformatics course is feasible for biology undergraduates.
  • A hands-on, programming-centric approach can effectively enhance understanding of biomolecular structure and bioinformatics.
  • This educational strategy offers a valuable alternative for bioinformatics training.