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Introduction to Metabolism

Introduction to Metabolism

Metabolism encompasses all biochemical reactions in a living organism, facilitating both the breakdown and synthesis of biomolecules. These metabolic processes are categorized into catabolic and anabolic pathways, which operate in a coordinated manner to ensure energy balance and cellular function.Catabolic Pathways and Energy ReleaseCatabolic pathways involve the breakdown of complex macromolecules such as carbohydrates, lipids, and proteins into smaller structures like monosaccharides, fatty...

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Carbohydrate Metabolism

Carbohydrate Metabolism

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The pentose phosphate pathway (PPP) operates in parallel with glycolysis, facilitating the metabolism of both pentoses and glucose. This pathway consists of two distinct phases: the oxidative and non-oxidative phases. While it does not directly generate ATP, the intermediates formed during the process can integrate into glycolysis, contributing to cellular energy metabolism when required.Oxidative Phase: NADPH ProductionThe oxidative phase of the pentose phosphate pathway is primarily...

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Related Experiment Video

Updated: Jun 1, 2026

A Web Tool for Generating High Quality Machine-readable Biological Pathways

A Web Tool for Generating High Quality Machine-readable Biological Pathways

Published on: February 8, 2017

Databases of metabolic pathways.

Vladimir A Likić¹

¹Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, 30 Flemington Road, Parkville 3010, Australia. vlikic@unimelb.edu.au.

Biochemistry and Molecular Biology Education : a Bimonthly Publication of the International Union of Biochemistry and Molecular Biology

|June 4, 2011

Summary

Bioinformatics advances have revolutionized metabolic pathway analysis. This study reviews KEGG and BioCyc databases, highlighting their digital advantages for biochemistry and molecular biology research.

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Area of Science:

Biochemistry
Molecular Biology
Bioinformatics

Background:

Metabolic pathway studies traditionally relied on complex printed charts.
Bioinformatics has transformed the management and visualization of metabolic pathway data.
Digital databases offer superior flexibility, query capabilities, and dynamic map generation compared to static charts.

Purpose of the Study:

To review advanced metabolic pathway databases.
To highlight the benefits of digital resources for metabolic studies.
To present the structure and background of KEGG and BioCyc.

Main Methods:

Review of publicly available metabolic pathway databases.
Focus on the Kyoto Encyclopedia of Genes and Genomes (KEGG).
Emphasis on the BioCyc collection of pathway/genome databases.

Main Results:

KEGG and BioCyc represent significant advances in metabolic pathway information management.
Digital databases allow for dynamic generation of pathway maps.
BioCyc exemplifies a collaborative effort to standardize metabolic pathway representation.

Conclusions:

Freely available internet-based metabolic databases are crucial for modern research.
KEGG and BioCyc offer powerful, flexible tools for studying metabolic pathways.
BioCyc's unified representation aids in comparative and systems biology.