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Apomyoglobin mutants with single point mutations at val10 can form amyloid structures at permissive temperature

N S Katina1, N B Ilyina, I A Kashparov

  • 1Institute of Protein Research, Russian Academy of Sciences, Pushchino, Moscow Region.

Biochemistry. Biokhimiia
|June 7, 2011
PubMed
Summary

Protein structural destabilization, not residue hydrophobicity, influences amyloid formation at permissive temperatures. This finding is crucial for understanding amyloid diseases.

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