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Hypothyroidism in the elderly: diagnostic pitfalls illustrated by a case report
Monica Maselli1, Eminè Meral Inelmen, Valter Giantin
1Department of Medicine and Surgical Sciences, Geriatrics Division, University of Padua, Via Giustiniani 2, 35128 Padova, Italy. monica.maselli@unipd.it
Hypothyroidism in the elderly is often missed due to non-specific symptoms. Routine thyroid-stimulating hormone testing is suggested for early diagnosis in older adults.
Area of Science:
- Geriatrics
- Endocrinology
- Internal Medicine
Background:
- Hypothyroidism diagnosis in the elderly is challenging due to non-specific clinical presentations.
- Symptoms often mimic normal aging or other comorbidities, leading to delayed diagnosis.
Observation:
- A case of primary hypothyroidism presented with asthenia, bradycardia, pleural effusions, hyponatremia, and worsening renal/respiratory insufficiency.
- These symptoms were initially attributed to aging, Parkinson's disease, and COPD.
Findings:
- Treatment with levothyroxine and liothyronine led to significant clinical improvement.
- Observed were increased reactivity, improved voice, resolved pleural effusion and bradycardia, normalized sodium, and improved renal function.
Implications:
- The non-specific nature of hypothyroidism symptoms in the elderly necessitates consideration for routine thyroid-stimulating hormone screening.
- Early diagnosis and treatment can significantly improve patient outcomes and quality of life in geriatric populations.
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