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Published on: September 26, 2018
[Factors associated with uncontrolled hypertension in patients with and without cardiovascular disease]
Alberto Cordero1, Vicente Bertomeu-Martínez, Pilar Mazón
1Departamento de Cardiología, Hospital Universitario de San Juan, 3550 Sant Joan d'Alacant, Alicante, Spain. acorderofort@gmail.com
Insights
Nearly half of patients with hypertension have uncontrolled blood pressure (BP). Lifestyle factors like obesity and smoking are independently linked to poor BP control, even in those with cardiovascular disease (CVD).
Area of Science:
- Cardiology
- Hypertension Research
- Public Health
Context:
- Hypertension is a leading modifiable risk factor for cardiovascular disease (CVD).
- Effective blood pressure (BP) control remains a challenge, particularly in patients with existing CVD.
- Understanding BP control rates and associated risk factors is crucial for clinical practice.
Purpose:
- To determine the rate of blood pressure (BP) control in a large cohort of hypertensive patients.
- To identify risk factors associated with uncontrolled BP, both in patients with and without cardiovascular disease (CVD).
Summary:
- A multicenter registry of 10,743 hypertensive patients found 55.4% achieved controlled BP (<140/90 mmHg).
- Uncontrolled BP was associated with male sex, active smoking, obesity, diabetes, and higher levels of glucose, cholesterol, LDL, and uric acid.
- Obesity and current smoking were independent predictors of uncontrolled BP, irrespective of CVD status.
Impact:
- Findings highlight the significant proportion of hypertensive patients with suboptimal BP control.
- Emphasizes the critical role of lifestyle modifications, specifically smoking cessation and weight management, in improving hypertension management.
- Informs targeted interventions for high-risk populations, including those with established cardiovascular disease.
Introduction And Objectives:
Hypertension is one of the most prevalent and poorly controlled risk factors, especially in patients with established cardiovascular disease (CVD). The aim of this study was to describe the rate of blood pressure (BP) control and related risk factors.
Methods:
Multicenter, cross-sectional and observational registry of patients with hypertension recruited from cardiology and primary care outpatient clinics. Controlled BP defined as <140/90 mmHg.
Results:
55.4% of the 10 743 patients included had controlled BP and these had a slightly higher mean age. Patients with uncontrolled BP were more frequently male, with a higher prevalence of active smokers, obese patients, and patients with diabetes. The rate of controlled BP was similar in patients with or without CVD. Patients with uncontrolled BP had higher levels of blood glucose, total cholesterol, low density lipoproteins and uric acid. Patients with uncontrolled BP were receiving a slightly higher mean number of antihypertensive drugs compared to patients with controlled BP. Patients with CVD were more frequently receiving a renin-angiotensin-aldosterone axis inhibitor: 83.5% vs. 73.2% (P<.01). Multivariate analysis identified obesity and current smoking as independently associated with uncontrolled BP, both in patients with or without CVD, as well as relevant differences between the two groups on other factors.
Conclusions:
Regardless of the presence of CVD, 55% of hypertensive patients had controlled BP. Lifestyle and diet, especially smoking and obesity, are independently associated with lack of BP control. Full English text available from: www.revespcardiol.org.
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Physiological Factors:
Hypertension and Regulation of Blood Pressure
Hypertension I: Introduction
Hypertension IV: Drug Therapy and Lifestyle Modifications
Hypertension III: Clinical Manifestations and Diagnostic Studies
Hypertension II: Pathophysiology