Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Venous Thrombosis I: Introduction

Venous Thrombosis I: Introduction

Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...

Pulmonary Embolism I: Introduction

Pulmonary Embolism I: Introduction

A blood clot, or thrombus, is a semi-solid mass composed of fibrin, platelets, and red blood cells. When it forms within a vessel, it can obstruct blood flow, known as thrombosis. If part of the clot detaches, it becomes an embolus that can travel and block distant vessels. When this occurs in the pulmonary arteries, it causes a condition known as pulmonary embolism (PE).Origin and ImpactMost often, the embolus originates from a thrombus in the deep veins of the lower limbs, a condition called...

Pulmonary Embolism I: Introduction

Pulmonary Embolism I: Introduction

Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...

Venous Thrombosis III: Interprofessional Care

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...

Disorders of Hemostasis

Disorders of Hemostasis

Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

miR-146a Mimic Therapy Protects Against Platelet-Mediated Thrombosis.

Molecular therapy : the journal of the American Society of Gene Therapy·2026

Same author

Comprehensive transcript and protein profiling reveals ERα rather than ERβ as the predominant estrogen receptor in human endometriotic lesions.

Communications biology·2026

Same author

Lysosomal phosphoinositide turnover acts upstream of RagGTPase-mTORC1 and controls muscle growth.

Nature metabolism·2026

Same author

First-Trimester Down Syndrome Screening in Renal-Transplanted Pregnant Women: Blood Creatinine Levels Impact False-Positive Rate.

Prenatal diagnosis·2026

Same author

Balloon plus oxytocin or oral misoprostol for labour induction in prelabour rupture of membranes (PROM): protocol for a randomised controlled trial (RUBAPRO2).

BMJ open·2026

Same author

[Delivery of twin pregnancies: Guidelines from the College of French Gynecologists and Obstetricians].

Gynecologie, obstetrique, fertilite & senologie·2026

Search research articles

Related Experiment Videos

Essential thrombocythemia and pregnancy.

Marie-Cécile Valera¹, Olivier Parant, Christophe Vayssiere

¹INSERM, U1048, Université Toulouse 3, I2MC, Equipe 9, CHU-Rangueil, Avenue Jean Poulhès BP84225, 31432 Toulouse Cedex 04, France.

European Journal of Obstetrics, Gynecology, and Reproductive Biology

|June 7, 2011

Summary

Essential thrombocythaemia (ET) in women of childbearing potential increases risks for pregnancy complications. Management strategies are crucial for improved fetal and maternal outcomes in these patients.

Related Experiment Videos

Area of Science:

Hematology
Reproductive Medicine
Oncology

Background:

Essential thrombocythaemia (ET) is a myeloproliferative neoplasm.
ET is characterized by high platelet counts and risks of bleeding or clotting.
ET is the most common myeloproliferative neoplasm in young women, posing unique challenges due to childbearing potential.

Purpose of the Study:

To review the literature on pregnancy outcomes in women with ET.
To discuss the risks of fetal and maternal complications associated with ET during pregnancy.
To provide recommendations for managing pregnancy in patients with ET.

Main Methods:

Literature review of studies on pregnancy and ET.
Analysis of reported fetal and maternal complications.
Synthesis of management recommendations from existing literature.

Main Results:

ET in pregnancy is associated with an increased risk of fetal complications, most commonly first-trimester spontaneous abortion.
Less frequent fetal complications include recurrent abortion, fetal growth restriction, stillbirth, and placental abruption.
Maternal complications are rare but can include thromboembolic and bleeding events.

Conclusions:

Pregnancy in women with Essential thrombocythaemia carries significant risks.
Careful monitoring and management are essential to mitigate complications.
Evidence-based recommendations can guide the care of pregnant patients with ET.