A case of midgut malrotation presenting as multiple afebrile seizures

Related Experiment Video

Updated: Jun 1, 2026

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy
09:57

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy

Published on: September 20, 2024

Jung-Rim Yoon1, Su Jeong You

  • 1Department of Pediatrics, Inje University Sanggye Paik Hospital, Nowon-gu, Seoul, South Korea.

Brain & Development
|June 7, 2011
PubMed

Insights

Infantile seizures linked to gastrointestinal issues may resolve with surgical correction of midgut malrotation. This case highlights the importance of evaluating gastrointestinal abnormalities in infants with unexplained seizures.

Area of Science:

  • Pediatric Neurology
  • Gastroenterology
  • Surgical Innovation

Background:

  • Provoked seizures are a frequent pediatric concern with diverse causes.
  • The association between benign infantile seizures and gastrointestinal tract abnormalities is infrequently reported.
  • Midgut malrotation is a congenital anomaly requiring surgical intervention.

Observation:

  • A 3-month-old infant experienced recurrent afebrile seizures.
  • Electroencephalogram (EEG) revealed significant abnormalities.
  • The infant was diagnosed with midgut malrotation.

Findings:

  • Surgical correction of the midgut malrotation led to complete seizure resolution.
  • Post-operative EEG monitoring showed normalization of brain activity.
  • The infant's symptoms significantly improved following surgical intervention.

Implications:

  • This case suggests a potential link between gastrointestinal abnormalities, specifically midgut malrotation, and infantile seizures.
  • It underscores the necessity of considering gastrointestinal evaluations in pediatric patients presenting with unexplained seizures and gastroenteritis symptoms.
  • Early surgical intervention for midgut malrotation may offer a curative approach for associated neurological symptoms in infants.

More Related Videos

Multi-system Monitoring for Identification of Seizures, Arrhythmias and Apnea in Conscious Restrained Rabbits10:25

Multi-system Monitoring for Identification of Seizures, Arrhythmias and Apnea in Conscious Restrained Rabbits

Published on: March 27, 2021

Related Concept Videos

Seizures: Classification01:13

Seizures: Classification

Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Seizures l: Introduction01:20

Seizures l: Introduction

Understanding seizures and epilepsy relies on key definitions that help in recognizing, classifying, and managing these disorders. These definitions provide a framework for recognizing, classifying, and managing seizure disorders.DefinitionsA seizure is a sudden, abnormal burst of electrical activity in the brain that can cause changes in awareness, movement, sensation, or behavior, depending on the area involved. Epilepsy is a chronic condition characterized by recurrent, unprovoked seizures,...
Epilepsy ll: Types01:22

Epilepsy ll: Types

Recurrent seizures, stemming from abnormal electrical activity in the brain, are the defining characteristic of epilepsy, a chronic neurological condition. Because seizure features vary greatly, epilepsy is classified using two systems: by seizure type and by epilepsy syndromes. These classifications enable clinicians to describe seizure patterns and select suitable treatment strategies.I. Classification by Seizure Type1. Focal EpilepsyFocal epilepsy begins in one hemisphere of the brain.
Seizures ll: Types01:19

Seizures ll: Types

Seizures are sudden bursts of abnormal electrical discharge in the brain that interfere with normal function. They are commonly divided into three groups: focal seizures, generalized seizures, and other types that do not fit neatly into either category.Focal SeizuresFocal seizures begin in a single brain region. When awareness is preserved, they are called focal aware seizures and may cause sensations such as tingling, unusual smells, or flashing lights. When awareness is impaired, they are...
Encephalitis l: Introduction01:19

Encephalitis l: Introduction

Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...
Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...