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Related Concept Videos

Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
Cancer Vaccines01:30

Cancer Vaccines

Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...

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Updated: Jun 1, 2026

Experimental Melanoma Immunotherapy Model Using Tumor Vaccination with a Hematopoietic Cytokine
09:15

Experimental Melanoma Immunotherapy Model Using Tumor Vaccination with a Hematopoietic Cytokine

Published on: February 24, 2023

Cancer immunotherapy.

Richard L White1, Asim Amin

  • 1Division of Surgical Oncology, Carolinas Medical Center, Blumenthal Cancer Center, 1025 Morehead Medical Drive, Suite 600, Charlotte, NC 28204, USA. Richard.White@carolinashealthcare.org

Surgical Oncology Clinics of North America
|June 7, 2011
PubMed
Summary
This summary is machine-generated.

Immune-based cancer therapies, including cytokine therapy and therapeutic cancer vaccines, are increasingly common and safe. Oncologists must understand monoclonal antibodies for cancer treatment, including their uses and side effects.

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Co-Culture In Vitro Systems to Reproduce the Cancer-Immunity Cycle
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Last Updated: Jun 1, 2026

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Flow Cytometry-Based Isolation and Therapeutic Evaluation of Tumor-Infiltrating Lymphocytes in a Mouse Model of Pancreatic Cancer
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Flow Cytometry-Based Isolation and Therapeutic Evaluation of Tumor-Infiltrating Lymphocytes in a Mouse Model of Pancreatic Cancer

Published on: January 17, 2025

Area of Science:

  • Oncology
  • Immunotherapy

Background:

  • Immune-based therapies are now standard in cancer treatment.
  • Cytokine therapy (interferon, interleukin-2) is safe for community use.
  • Monoclonal antibodies targeting cell growth and immune response are widely used.

Purpose of the Study:

  • To review the current landscape of immune-based cancer therapies.
  • To highlight the importance of understanding monoclonal antibody applications and toxicities for oncologists.

Main Methods:

  • Review of current literature and FDA approvals for cancer immunotherapies.
  • Discussion of established cytokine therapies and novel therapeutic cancer vaccines.
  • Overview of monoclonal antibody mechanisms and clinical relevance.

Main Results:

  • Sipuleucel-T, a therapeutic cancer vaccine, is FDA-approved for advanced prostate cancer.
  • Cytokine therapies demonstrate safety in community settings.
  • Monoclonal antibodies are integral to modern cancer care.

Conclusions:

  • Oncologists require comprehensive knowledge of immune-based therapies, including monoclonal antibodies.
  • Familiarity with indications, contraindications, and toxicities of these treatments is essential for effective patient care.