Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jun 1, 2026

Quantification of Global Diastolic Function by Kinematic Modeling-based Analysis of Transmitral Flow via the Parametrized Diastolic Filling Formalism

Quantification of Global Diastolic Function by Kinematic Modeling-based Analysis of Transmitral Flow via the Parametrized Diastolic Filling Formalism

Published on: September 1, 2014

[Diastolic retrograde arterial flow: preliminary report].

M J Mc Loughlin¹, S Mc Loughlin, J Milei

¹Instituto de Investigaciones Cardiológicas Alberto C. Taquini (ININCA) UBA-CONICET, Buenos Aires, Argentina. santimcl@gmail.com

|June 7, 2011

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Nausea and vomiting in a colorectal ERAS program: Impact on nutritional recovery and the length of hospital stay.

Clinical nutrition ESPEN·2019

Same author

No lower bacterial adhesion for ceramics compared to other biomaterials: An in vitro analysis.

Orthopaedics & traumatology, surgery & research : OTSR·2018

Same author

Left ventricular hypertrophy does not prevent heart failure in experimental hypertension.

International journal of cardiology·2017

Same author

Influence of single-dose intravenous tranexamic acid on total hip replacement : A study on transfusions, collateral complications, and readmissions.

Der Orthopade·2016

Same author

Plasma Enalapril Kinetics of Two Modified Formulations Tested in Healthy Volunteers. A Pilot Trial Searching for an Optimum Blood Pressure Control.

Journal of the American Society of Hypertension : JASH·2016

Same author

Ozonetherapy protects from in-stent coronary neointimal proliferation. Role of redoxins.

International journal of cardiology·2016

Holodiastolic reflux, a blood flow pattern typically seen in disease, was observed in the brachial artery of healthy individuals when their arms were raised. This physiological phenomenon in normal patients warrants further study.

Area of Science:

Vascular Ultrasound
Hemodynamics
Physiology

Context:

Holodiastolic arterial blood flow is generally considered pathological.
Previous observations suggest this flow pattern may occur in healthy individuals under specific conditions.
The brachial artery is a key vessel for assessing upper extremity circulation.

Purpose:

To investigate the frequency and characteristics of holodiastolic arterial blood flow in the brachial artery of healthy subjects.
To determine if arm elevation influences brachial artery blood flow patterns.
To differentiate physiological holodiastolic flow from pathological conditions.

Summary:

Ten healthy volunteers underwent ultrasound assessment of the brachial artery.
Measurements were taken in supine position, with the arm raised above horizontal, and after returning to supine.

More Related Videos

Ultrasound Assessment of Flow-Mediated Dilation of the Brachial and Superficial Femoral Arteries in Rats

Ultrasound Assessment of Flow-Mediated Dilation of the Brachial and Superficial Femoral Arteries in Rats

Published on: November 3, 2016

Related Experiment Videos

Last Updated: Jun 1, 2026

Quantification of Global Diastolic Function by Kinematic Modeling-based Analysis of Transmitral Flow via the Parametrized Diastolic Filling Formalism

Quantification of Global Diastolic Function by Kinematic Modeling-based Analysis of Transmitral Flow via the Parametrized Diastolic Filling Formalism

Published on: September 1, 2014

Ultrasound Assessment of Flow-Mediated Dilation of the Brachial and Superficial Femoral Arteries in Rats

Ultrasound Assessment of Flow-Mediated Dilation of the Brachial and Superficial Femoral Arteries in Rats

Published on: November 3, 2016

Mid- and end-diastolic retrograde flow (holodiastolic reflux) was observed in 8/10 participants when their arms were raised, but not in baseline or post-raising measurements.

Impact:

Demonstrates that holodiastolic reflux can be a normal physiological response in healthy individuals.
Suggests that arm position significantly impacts brachial artery hemodynamics.
Provides a basis for further research into the clinical significance of this finding in various pathological states.