Related Experiment Video
Updated: Jun 1, 2026

An Integrated Approach for Microprotein Identification and Sequence Analysis
Published on: July 12, 2022
Realignment capability of the nCPMG sequence
P Le Roux1, G McKinnon, Y-F Yen
1Global Applied Science Laboratory, GE Healthcare, Palaiseau, France. patrick.leroux@med.ge.com
Abstract:
The nCPMG sequence is based on a particular phase modulation of the refocusing pulse train, and was originally designed for rendering the spin echo amplitude insensitive to the initial magnetization phase. This pulse sequence has the peculiarity of being easily invertible, which enables perfect driven equilibrium experiments, in the absence of relaxation. This magnetization 'realignment' is effective for all three components. Hence the overall operation is transparent. Supporting theory is presented here, together with the first direct experimental proof of the claim. The experiment shows that, with the present stabilization sequence, perfect realignment is indeed made possible for a range of refocusing pulse nutation angles from 130° to 230°.
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