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Interaction between X-ray- and restriction endonuclease-induced lesions in the formation of chromosomal aberrations
C Tanzarella1, R De Salvia, F Degrassi
1Centro di Genetica Evoluzionistica del CNR, c/o Dipartimento Darwin, Università La Sapienza, Rome, Italy.
Mutation Research
|July 1, 1990
Abstract:
Experiments were performed to analyze the possible interaction between lesions induced by X-rays and restriction endonucleases in the production of chromosome-type exchanges. A stronger interaction was found between X-rays and the AluI-induced 'blunt termini' lesions than between X-rays and the BamHI-induced 'cohesive termini' lesions.