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Updated: Jun 1, 2026

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Vitrification of In Vitro Matured Oocytes Collected from Adult and Prepubertal Ovaries in Sheep
Published on: July 10, 2021
Effect of cyclosporine pretreatment on mitochondrial function in vitrified bovine mature oocytes
Xue-Ming Zhao1, Wei-Hua Du, Dong Wang
1Embryo Biotechnology and Reproduction Laboratory, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, People's Republic of China.
Fertility and Sterility
|June 7, 2011
Abstract:
Vitrification had a significantly negative impact on the mitochondrial function of bovine oocytes. However, 40 μg/mL cyclosporine pretreatment before vitrification contributed greatly to maintaining mitochondrial membrane potential and adenosine triphosphate content, decreasing reactive oxygen species level, and thereby increasing the developmental ability of vitrified oocytes.
