Related Experiment Video
Updated: Jun 1, 2026

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice
Published on: May 2, 2025
Rhabdomyolysis without detectable myoglobulinuria due to severe hypophosphatemia in diabetic ketoacidosis
Alev Oguz Kutlu1, Cengiz Kara, Semra Cetinkaya
1Dr Sami Ulus Children's Hospital, Pediatric Endocrinology Clinic, Ankara, Turkey. alevkutlu64@yahoo.com.tr
Abstract:
Clinical signs of hypophosphatemia, even when severe, are rare in diabetic ketoacidosis despite their high frequency in this condition. This article presents a patient with rhabdomyolysis due to severe hypophosphatemia, where the level of serum phosphorus was observed to be as low as 0.42 mg/dL on the 16th hour of ketoacidosis treatment. The patient developed acute tubular necrosis due to rhabdomyolysis, but there was no blood reaction in the urine, and the creatine kinase increased to 1200 U/L. The patient was treated without dialysis and was cured after a polyuria period of 2 months after the oliguric period.
Related Concept Videos
Diabetic Ketoacidosis ll: Pathophysiology
Diabetic Ketoacidosis l: Introduction
Hyperosmolar Hyperglycemic State
Diabetic Nephropathy
Hyperglycemia
Complications of Diabetes Mellitus