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An Improved Method for the Preparation of Type I Collagen From Skin
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[The treatment of scleroderma with the enzyme preparation collalysine]

S I Dovzhanskiĭ, A I Zav'ialov

    Vestnik Dermatologii I Venerologii
    |January 1, 1990
    PubMed

    Abstract:

    Examinations of 42 patients with local scleroderma have revealed increased hydroxyproline and glycosaminoglycane excretion and impaired cellular and humoral immunity, these shifts correlating with the type and severity of the disease. Collalysin therapy resulted in a good clinical effect and improvement of the immune and metabolic parameters.

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