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Related Experiment Video

Updated: Jun 1, 2026

Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping
10:25

Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping

Published on: September 25, 2019

Red cell distribution width does not predict stroke severity or functional outcome.

George Ntaios1, Ozgur Gurer, Mohamed Faouzi

  • 1Neurology Service, Centre Hospitalier Universitaire Vaudois, University of Lausanne, Lausanne, Switzerland. ntaiosgeorge@yahoo.gr

International Journal of Stroke : Official Journal of the International Stroke Society
|June 8, 2011
PubMed
Summary

Red cell distribution width (RDW) is not a predictor of stroke severity or functional outcome in acute ischemic stroke patients. Several factors, including age and hemoglobin, influence RDW levels in this population.

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Area of Science:

  • Neurology
  • Hematology
  • Clinical Medicine

Background:

  • Red cell distribution width (RDW) is a known predictor of mortality in stroke patients.
  • Elevated RDW is observed in individuals with stroke compared to controls.
  • Limited data exists on RDW's association with acute ischemic stroke severity and functional outcomes.

Purpose of the Study:

  • To investigate the relationship between RDW during acute ischemic stroke and stroke severity.
  • To determine if RDW predicts functional outcome in acute ischemic stroke.
  • To identify the primary determinants of RDW in patients experiencing acute ischemic stroke.

Main Methods:

  • Analysis of data from the Acute Stroke Registry and Analysis of Lausanne (2003-2008).
  • RDW measurement using Sysmex XE-2100 automated cell counter upon admission.

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Last Updated: Jun 1, 2026

Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping
10:25

Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping

Published on: September 25, 2019

  • Univariate and multivariate robust regression analyses to assess RDW's effect on severity and outcome.

    • Main Results:

    • RDW showed univariate association with NIHSS and functional outcome (poor outcome).
    • This association was not significant in multivariate analysis.
    • Independent determinants of RDW included prehospital Rankin score, serum creatinine, hemoglobin, mean platelet volume, age, low ejection fraction, and antihypertensive treatment.

    Conclusions:

    • RDW assessed in the early phase of acute ischemic stroke does not predict stroke severity.
    • RDW does not predict functional outcome in acute ischemic stroke patients.