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Published on: May 10, 2024
Eosinophilic gastrointestinal disorders in infants: a Japanese case series
Yoshiyuki Yamada1, Akira Nishi, Yoshifumi Ebara
1Division of Allergy and Immunology, Gunma Children's Medical Center, Shibukawa, Japan. yamaday@gcmc.pref.gunma.jp
Background:
Eosinophilic gastrointestinal disorders (EGIDs) are disorders characterized by primary eosinophil inflammation in the gastrointestinal tract. There are a small number of reports of eosinophil infiltration in gastrointestinal tracts presenting as EGIDs in infants. In this study, we present Japanese cases of EGIDs in infants.
Methods:
Five patients diagnosed with or strongly suspected to have EGIDs in our hospital from 2008 to 2010 were reviewed. Radiographic contrast enema examinations and/or endoscopies were performed in 4 and 3 patients, respectively.
Results:
There were patients with eosinophilic colitis (1 suspected and 2 biopsy-proven), a patient who was suspected of having allergic eosinophilic enterocolitis, and a patient with eosinophilic gastroenteritis associated with pediatric hypereosinophilic syndrome.
Conclusions:
The causes and clinical findings of patients with intestinal eosinophil inflammation vary. Therefore, deliberate examination and observation are important for patients with infantile EGID.
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