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Updated: Jun 1, 2026

A Mouse Model of Orthopedic Surgery to Study Postoperative Cognitive Dysfunction and Tissue Regeneration
Published on: February 27, 2018
[Long-term consequences of postoperative delirium].
A Ihrig1, R von Haken, M Mieth
1Sektion Psychoonkologie, Klinik für Allgemeine Innere Medizin und Psychosomatik, Universitätsklinikum Heidelberg, INF 410, 69120, Heidelberg, Deutschland. andreas.ihrig@med.uni-heidelberg.de
Postoperative delirium in intensive care units can lead to long-term anxiety and sleep issues. Early detection and intervention, like psychotherapy, may prevent lasting psychological distress.
Area of Science:
- Medical Psychology
- Neuroscience
- Surgical Oncology
Background:
- Reconstruction of the anterior floor of the mouth is a complex surgical procedure often following tumor resection.
- Postoperative delirium is a known complication in intensive care settings, characterized by altered mental status.
- Long-term psychological sequelae after major surgery are increasingly recognized.
Observation:
- A patient developed anxiety and sleeping problems nine months after anterior floor of the mouth reconstruction.
- These psychological symptoms were linked to an undiagnosed episode of postoperative delirium with hallucinations.
- The delirium episode occurred during the initial intensive care unit stay following surgery.
Findings:
- A single psychotherapy session nine months post-surgery significantly alleviated the patient's anxiety and sleep disturbances.
- The patient's long-term psychological distress stemmed from an unrecognized delirium event.
- Proactive inquiry and patient education regarding delirium symptoms are crucial.
Implications:
- Screening for and informing patients about delirium symptoms in intensive care units may prevent chronic psychological distress.
- Early identification of delirium could mitigate the risk of persistent mental health issues after major surgery.
- This case highlights the importance of recognizing and managing delirium to improve long-term patient outcomes.
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