High frequency of cardiac and behavioral complaints as presenting symptoms of hyperthyroidism in children

Lindsey A Loomba-Albrecht1, Andrew A Bremer, Dennis M Styne

  • 1Department of Pediatrics, Division of Endocrinology, University of California Davis Medical Center, Sacramento, CA 95817-2208, USA. lindsey.albrecht@ucdmc.ucdavis.edu

Insights

Cardiac symptoms are the most common chief complaint in children with hyperthyroidism. However, mood and behavior disturbances are also frequent, though often overlooked, leading to delayed diagnosis.

Area of Science:

  • Pediatrics
  • Endocrinology
  • Child Health

Background:

  • Limited data exists on the primary reasons children seek medical care for hyperthyroidism.
  • Atypical presentations can complicate early diagnosis and increase patient morbidity.

Observation:

  • A retrospective review analyzed medical records of 76 pediatric patients diagnosed with hyperthyroidism.
  • The study focused on characterizing chief complaints and presenting symptoms at initial medical encounters.

Findings:

  • Cardiac symptoms were the most frequent chief complaint, reported by 23% of patients.
  • Mood and behavioral disturbances were present in 21% of cases but rarely identified as the primary complaint (6%).

Implications:

  • This research highlights the diverse initial presentations of pediatric hyperthyroidism.
  • Recognizing cardiac and behavioral symptoms is crucial for prompt diagnosis and improved patient outcomes.
Abstract

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