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Cyclic CMP (cytidine 3',5'-monophosphate) suppresses changes in human sperm amplitude of lateral head displacement
P J Chan1, D R Tredway, I Henig
1Dept of Gynecology and Obstetrics, Loma Linda University School of Medicine, California 92354.
Experientia
|July 15, 1990
Abstract:
The dibutyryl analog of cCMP suppressed sperm amplitude of lateral head displacement and hyperactivation. Sperm motility was inhibited by dibutyryl cCMP with a shift toward less linear trajectory sperm movements. The results suggest a role of cCMP as an inhibitory signal on sperm motility patterns related to sperm capacitation.