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Workflow and Tools for Crystallographic Fragment Screening at the Helmholtz-Zentrum Berlin
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Antibody fragments as tools in crystallography

L Griffin1, A Lawson

  • 1Department of Structural Biology, UCB, Slough, UK.

Clinical and Experimental Immunology
|June 9, 2011
PubMed
Summary

Antibody fragments act as crystallization chaperones, enabling structural determination of difficult-to-crystallize proteins for drug discovery. This technique aids in designing new chemical entities for therapeutic development.

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