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Updated: Jun 1, 2026

A Novel Use of Three-dimensional High-frequency Ultrasonography for Early Pregnancy Characterization in the Mouse
Published on: October 24, 2017
[The role of three-dimensional ultrasonography in assisted reproduction]
T Zácková1, T Mardesic, L Krofta
1Ustav pro péci o matku a dite, Praha.
Objective:
Clarifying the role of three-dimensional transvaginal sonography in diagnosis sterility and assisted reproduction treatment.
Design:
Review.
Setting:
Institute for the Care of Mother and Child, Department of IVF, Charles University, Prague.
Methods:
Study of current literature.
Summary:
With arrised frequency of ovarian, uterus and another pelvic patologies remains the three-dimensional transvaginal sonography in diagnosis of sterility women very actual in the fields of reproductive medicine. Actually the assessment of ovarian reserve belong to the essentials investigations in the diagnosis of primary and secondary sterility at this time. The advance in the three-dimensional transvaginal sonography allows to assess the endometrial volume, echogenity, endometrial vascularity and endometrial receptivity. There is a significant importance of 3D power Doppler angiography by measurement of folicular and ovarian vascularity with three indices (VI, FI, VFI) and provides the calculation of ovarian vascularity from the volume. New Sono-Automatic Volume Calculation (Sono-AVC) software that identifies and quantifies hypoechoic regions within a three-dimensional dataset and provides automatic estimation of their absolute dimensions, mean diameter and volume. An unlimited number of volumes can theoretically be quantified, which makes it an ideal tool for assessment of the ovarian volume and the antral follicle count (AFC) in women undergoing controlled ovarian stimulation.
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