Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Toxicity Testing in Animals01:23

Toxicity Testing in Animals

Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ventral hernia repair in patients with abdominal loss of domain: an observational study of one institution's experience.

Hernia : the journal of hernias and abdominal wall surgery·2017
Same author

Creation of a novel risk score for surgical site infection and occurrence after ventral hernia repair.

Hernia : the journal of hernias and abdominal wall surgery·2016
Same author

Effect of hernia size on operative repair and post-operative outcomes after open ventral hernia repair.

Hernia : the journal of hernias and abdominal wall surgery·2016
Same author

A validated, risk assessment tool for predicting readmission after open ventral hernia repair.

Hernia : the journal of hernias and abdominal wall surgery·2015
Same author

The effect of TISSEEL fibrin sealant on seroma formation following complex abdominal wall hernia repair: a single institutional review and derived cost analysis.

Hernia : the journal of hernias and abdominal wall surgery·2015
Same author

EPA struggles to implement pesticide law.

Environmental science & technology·2011

Related Experiment Video

Updated: Jun 1, 2026

Screening for Endocrine Activity in Water Using Commercially-available In Vitro Transactivation Bioassays
08:00

Screening for Endocrine Activity in Water Using Commercially-available In Vitro Transactivation Bioassays

Published on: December 4, 2016

Endocrine disrupter screening strategy to involve two-tiered testing

C M Cooney

    Environmental Science & Technology
    |June 10, 2011
    PubMed
    Summary

    No abstract available in PubMed .

    More Related Videos

    In vivo Characterization of Endocrine Disrupting Chemical Effects via Thyroid Hormone Action Indicator Mouse
    04:14

    In vivo Characterization of Endocrine Disrupting Chemical Effects via Thyroid Hormone Action Indicator Mouse

    Published on: October 6, 2023

    Methods to Test Endocrine Disruption in Drosophila melanogaster
    09:43

    Methods to Test Endocrine Disruption in Drosophila melanogaster

    Published on: July 3, 2019

    Related Experiment Videos

    Last Updated: Jun 1, 2026

    Screening for Endocrine Activity in Water Using Commercially-available In Vitro Transactivation Bioassays
    08:00

    Screening for Endocrine Activity in Water Using Commercially-available In Vitro Transactivation Bioassays

    Published on: December 4, 2016

    In vivo Characterization of Endocrine Disrupting Chemical Effects via Thyroid Hormone Action Indicator Mouse
    04:14

    In vivo Characterization of Endocrine Disrupting Chemical Effects via Thyroid Hormone Action Indicator Mouse

    Published on: October 6, 2023

    Methods to Test Endocrine Disruption in Drosophila melanogaster
    09:43

    Methods to Test Endocrine Disruption in Drosophila melanogaster

    Published on: July 3, 2019