Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Insulin, insulin sensitivity and hypertension.

P Ferrari1, P Weidmann

  • 1Medizinische Poliklinik, University of Bern, Switzerland.

Journal of Hypertension
|June 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

MCNPX internal dosimetry studies based on the NORMAN-05 voxel model.

Radiation protection dosimetry·2007
Same author

Monte Carlo evaluated parameters for internal dosimetry.

Radiation protection dosimetry·2007
Same author

Acid reflux into the oesophagus does not influence exercise-induced airway narrowing in bronchial asthma.

British journal of sports medicine·2007
Same author

Ouabain-dependent signaling in caveolae as a novel therapeutic target for hypertension.

Cellular and molecular biology (Noisy-le-Grand, France)·2007
Same author

Preliminary studies on neutron conversion coefficients calculated with MCNPX in NORMAN voxel phantom.

Radiation protection dosimetry·2007
Same author

Dementia and occupational therapy.

Archives of gerontology and geriatrics·2007

Insulin resistance and high insulin levels are linked to hypertension and cardiovascular issues. These conditions may contribute to the development of essential, obesity-associated, and diabetes-related hypertension and dyslipidemia.

Area of Science:

  • Endocrinology
  • Metabolic Syndrome
  • Cardiovascular Physiology

Background:

  • Tissue sensitivity to insulin is crucial for glucose metabolism and cardiovascular function.
  • Insulin resistance and hyperinsulinemia are prevalent in conditions like obesity, impaired glucose tolerance, and non-insulin-dependent diabetes mellitus.
  • Essential hypertension is often associated with insulin resistance, even without obesity or diabetes.

Purpose of the Study:

  • To explore the link between insulin resistance, hyperinsulinemia, and hypertension.
  • To investigate the potential role of insulin resistance and hyperinsulinemia in the development of various forms of hypertension and dyslipidemia.

Main Methods:

  • Review of existing evidence on insulin's effects on physiological and pathophysiological processes.

Related Experiment Videos

  • Analysis of the association between insulin sensitivity, insulin levels, and cardiovascular parameters.
  • Consideration of insulin's acute effects on sympathetic nervous activity, cation transport, and renal sodium reabsorption.

    • Main Results:

    • Decreased insulin sensitivity and/or hyperinsulinemia are common in hypertensive individuals.
    • Insulin resistance can lead to compensatory hyperinsulinemia.
    • Hyperinsulinemia also occurs in type 1 diabetes due to insulin treatment.

    Conclusions:

    • Insulin resistance and/or hyperinsulinemia may contribute to essential, obesity-associated, and diabetes-associated hypertension.
    • These metabolic disturbances may also promote dyslipidemia in affected individuals.
    • Understanding these links is vital for therapeutic interventions in metabolic and cardiovascular disorders.