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Related Concept Videos

Capillary Electrophoresis: Applications01:30

Capillary Electrophoresis: Applications

Capillary electrophoretic separations offer various modes, each with unique applications. These modes include capillary zone electrophoresis, capillary gel electrophoresis, capillary array electrophoresis, capillary isoelectric focusing, capillary isotachophoresis, micellar electrokinetic chromatography, and capillary electrochromatography.
Capillary zone electrophoresis (CZE) separates ionic components based on their electrophoretic mobility. It has been used to separate proteins, amino acids,...
Detergent Purification of Membrane Proteins01:18

Detergent Purification of Membrane Proteins

Detergents are used to purify the integral proteins of the membrane. The hydrophobic portion of the detergent can replace membrane phospholipids while solubilizing the membrane proteins. When detergent monomers reach a specific concentration in a solution called critical micelle concentration (CMC), they form micelles. Above CMC, the concentration of the detergent monomers remains in equilibrium with the micelle. The number of detergent monomers present in the CMC varies for each detergent, and...

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Related Experiment Video

Updated: Jun 1, 2026

Merging Ion Concentration Polarization between Juxtaposed Ion Exchange Membranes to Block the Propagation of the Polarization Zone
08:06

Merging Ion Concentration Polarization between Juxtaposed Ion Exchange Membranes to Block the Propagation of the Polarization Zone

Published on: February 23, 2017

Peer Reviewed: Membrane Preconcentration CE.

Q Yang, A J Tomlinson, S Naylor

    Analytical Chemistry
    |June 10, 2011
    PubMed
    Summary
    This summary is machine-generated.

    Researchers developed a novel method for sample preconcentration. This technique improves the initial concentration of analytes before analytical separation processes.

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    Last Updated: Jun 1, 2026

    Merging Ion Concentration Polarization between Juxtaposed Ion Exchange Membranes to Block the Propagation of the Polarization Zone
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    Published on: February 23, 2017

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    Paper-Based Preconcentration and Isolation of Microvesicles and Exosomes

    Published on: April 29, 2020

    Area of Science:

    • Analytical Chemistry
    • Separation Science

    Background:

    • Effective sample preconcentration is crucial for trace analysis.
    • Existing methods can be time-consuming or require complex instrumentation.

    Purpose of the Study:

    • To introduce a new, efficient approach for sample preconcentration.
    • To enhance sensitivity and reduce detection limits in analytical separations.

    Main Methods:

    • Development of a novel preconcentration technique.
    • Integration of the preconcentration step prior to chromatographic or electrophoretic separation.

    Main Results:

    • Demonstrated significant improvement in analyte preconcentration.
    • Showcased enhanced analytical performance compared to conventional methods.

    Conclusions:

    • The new approach offers a valuable tool for improving analytical sample preparation.
    • This method has the potential to advance trace analysis across various scientific disciplines.