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Prospective comparison of biopsy results from curettage and hysteroscopy in postmenopausal uterine bleeding
Dong Ock Lee1, Min Hyung Jung, Heung Yeol Kim
1Center for Uterine, National Cancer Center, Goyang-si, Korea.
Aim:
To evaluate the diagnostic accuracy of biopsy by dilatation and curettage in postmenopausal women with abnormal uterine bleeding.
Material And Methods:
A prospective observational study conducted with 112 consecutive postmenopausal women. Biopsy by dilatation and curettage was immediately followed by hysteroscopic biopsy and the histologic results were compared.
Results:
By curettage, although performed under anesthesia, 3/3 (100%) cases of endometrial hyperplasia were reported as normal proliferative endometrium. There were two endometrial cancers (1.8%) and one case was missed as normal endometrium by curettage. Among endometrial polyps, only 3/39 (7.7%) cases were diagnosed by curettage.
Conclusions:
In postmenopausal women with abnormal uterine bleeding, biopsy by curettage may be not reliable for evaluation of endometrial pathology.
