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Published on: July 27, 2022

CLSI releases updated Guideline for the Development of Immunohistochemical Assays

Melissa D'Archangelo, Stephen Hewitt, Max Robinowitz

    Applied Immunohistochemistry & Molecular Morphology : AIMM
    |June 10, 2011
    PubMed
    Abstract

    No abstract available in PubMed .

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    Immunocytochemistry (ICC) and immunohistochemistry (IHC) are techniques that use antibodies to check for specific proteins or antigens in a sample. The technique was first published by Albert Coons in 1941 to detect the presence of pneumococcal antigen in tissue sections from mice infected with Pneumococcus. Immunocytochemistry helps localization of proteins or antigens in individual cells like blood cells, stem cells, etc., while immunohistochemistry does the same for tissue samples.
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