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A somitic Wnt16/Notch pathway specifies haematopoietic stem cells

Wilson K Clements1, Albert D Kim, Karen G Ong

  • 1Department of Cellular and Molecular Medicine and Section of Cell and Developmental Biology, University of California at San Diego, 9500 Gilman Drive, La Jolla, California 92093-0380, USA.

Nature
|June 10, 2011
PubMed
Summary

Wnt16 signaling controls a new network for specifying hematopoietic stem cells (HSCs). This pathway is crucial for generating blood and immune cells, offering potential for future HSC therapies.

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