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Related Concept Videos

Papillary Dermis01:11

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Elastin is Responsible for Tissue Elasticity01:12

Elastin is Responsible for Tissue Elasticity

Elastic fiber contains the protein elastin along with lesser amounts of other proteins and glycoproteins. The main property of elastin is that it will return to its original shape after being stretched or compressed. Elastic fibers are prominent in elastic tissues found in skin and the elastic ligaments of the vertebral column.
Ligaments and tendons are made of dense regular connective tissue, but in ligaments not all fibers are parallel. Dense regular elastic tissue contains elastin fibers and...
Reticular Dermis01:15

Reticular Dermis

The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
Layers of Connective Tissue Proper01:21

Layers of Connective Tissue Proper

Fascia, a thin layer of fibrous connective tissue, is distributed throughout the body. It demarcates and forms a supportive covering over skeletal muscles, bones, blood vessels, and organs. There are three main types of facia— superficial fascia, deep fascia, and subserous fascia. These are all present at different depths in the body. Fascia reduces the friction and permits muscles, joints, and organs to easily slide against each other, facilitating movement of the body and preventing tearing...
Classification of Skeletal Muscle Fibers01:48

Classification of Skeletal Muscle Fibers

Skeletal muscles continuously produce ATP to provide the energy that enables muscle contractions. Skeletal muscle fibers can be categorized into three types based on differences in their contraction speed and how they produce ATP, as well as physical differences related to these factors. Most human muscles contain all three muscle fiber types, albeit in varying proportions.
Slow-Twitch Muscle Fibers
Slow oxidative, muscle fibers appear red due to large numbers of capillaries and high levels of...

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Related Experiment Video

Updated: Jun 1, 2026

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models
08:57

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models

Published on: May 17, 2024

Elastofibroma dorsi: A soft tissue masquerade.

Pauline H Go1, Michael C Meadows, Essel Marie B Deleon

  • 1Saint George's University, School of Medicine, Grenada, West Indies.

International Journal of Shoulder Surgery
|June 10, 2011
PubMed
Summary
This summary is machine-generated.

Elastofibroma dorsi (ED) is a rare soft tissue tumor. Typical MRI findings in elderly patients with bilateral subscapular masses may obviate the need for biopsy and excision.

Keywords:
Elastofibroma dorsifibromahemangiomalipomasarcomasoft tissue tumorsubscapular mass

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Last Updated: Jun 1, 2026

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models
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Stromal Vascular Fraction-enriched Fat Grafting for the Treatment of Symptomatic End-neuromata

Published on: November 23, 2017

Area of Science:

  • Orthopedics
  • Radiology
  • Pathology

Background:

  • Elastofibroma dorsi (ED) is a rare soft tissue tumor typically located in the subscapular region.
  • Its exact pathogenesis remains unclear, though mechanical microtrauma is a suspected cause.
  • ED predominantly affects elderly individuals, with a reported prevalence ranging from 2% to 24% in this demographic.

Observation:

  • A review of 330 reported cases (1980-present) revealed a 3.9:1 female-to-male ratio.
  • The mean age of affected individuals was 62 years (range 6-94 years).
  • Bilateral ED occurred in 164 patients, while 157 had unilateral presentation.

Findings:

  • Magnetic resonance imaging (MRI) is the preferred diagnostic modality for ED.
  • Typical MRI characteristics in elderly patients with bilateral subscapular masses can help avoid invasive procedures.
  • Complete surgical excision is curative, with rare recurrence.

Implications:

  • Accurate MRI interpretation can streamline diagnosis and management of ED.
  • Avoiding unnecessary biopsies and excisions in typical cases reduces patient morbidity.
  • Further research into ED pathogenesis may reveal novel therapeutic targets.