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Published on: February 6, 2019
Heavy drinking is associated with poor blood pressure control in the REasons for Geographic and Racial Differences in
Suzanne E Judd1, Leslie A McClure, Virginia J Howard
1Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, 1665 University Boulevard, Birmingham, AL 35294, USA. sejudd@uab.edu
Insights
Heavy alcohol consumption is linked to higher odds of hypertension, particularly in individuals with diabetes. The typical J-shaped alcohol-BP relationship was not observed, suggesting heavy drinkers should limit intake for better blood pressure control.
Area of Science:
- Cardiovascular Health
- Epidemiology
- Metabolic Disorders
Background:
- The relationship between alcohol intake and blood pressure (BP) often follows a J-shaped curve.
- This association requires examination in diverse populations, including mixed-race individuals and those with diabetes, who need strict BP management.
Purpose of the Study:
- To investigate the association between alcohol consumption and hypertension in a large, diverse cohort.
- To explore potential modifications of this relationship by diabetes status and gender.
Main Methods:
- Analysis of data from 30,239 participants aged 45+ in the REGARDS study.
- Collection of self-reported alcohol intake, medical history, and clinical measurements.
- Definition of diabetes and hypertension based on established clinical criteria.
Main Results:
- Heavy drinking was significantly associated with increased odds of hypertension (OR = 1.59; 95% CI = 1.37, 1.87) after adjusting for confounders.
- Diabetes and gender significantly modified the alcohol-hypertension association.
- The J-shaped relationship was absent in most subgroups, except for white females.
Conclusions:
- Heavy alcohol consumption is linked to a higher likelihood of hypertension.
- Individuals who are heavy drinkers may benefit from reducing alcohol intake to aid in hypertension management.
- The findings highlight the importance of considering alcohol intake in BP management strategies, especially in at-risk populations.
Abstract:
Alcohol intake has been shown to have a J-shaped association with blood pressure (BP). However, this association has not been examined in mixed race populations or in people with diabetes where tighter blood pressure control is recommended. Participants in the REGARDS study who were 45 years or older (n = 30,239) were included. Medical history (including self-reported alcohol intake) was collected by telephone while blood collection and clinical measurements were done during an in-home visit. We defined diabetes as use of medications and/or fasting glucose ≥ 126 mg/dL and hypertension as use of blood pressure lowering medications and/or BP ≥ 140/90 mmHg or BP ≥ 130/80 mmHg in people with diabetes. After adjustment for confounders, heavy drinking was associated with an increased odds of hypertension (OR = 1.59; 95% CI = 1.37, 1.87). Diabetes and gender significantly modified (interaction P < 0.05 for both) the association between alcohol use and hypertension, although heavy drinking remained associated with increased odds of hypertension in sub-group analyses. We did not observe the previously described J-shaped relationship in any sub-group except white females. These data suggest heavy alcohol consumption is associated with poor BP control and that heavy drinkers may want to consider limiting alcohol intake in order to manage hypertension.
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Hypertension occurs when blood pressure readings consistently exceed the normal range. It is diagnosed when systolic blood pressure (the top number, indicating pressure while the heart beats)...