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Updated: Jun 1, 2026
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Determining Membrane Protein Topology Using Fluorescence Protease Protection (FPP)
Published on: April 20, 2015
New tools in membrane protein determination
1Department of Biochemistry & Biophysics, University of California San Francisco, S-412C Genentech Hall, 600 16th Street, San Francisco, CA 94158-2517 USA.
F1000 Biology Reports
|June 10, 2011
Abstract:
The determination of membrane structures presents the structural biologist with many challenges; however, the last two years have seen major advances in our ability to resolve these structures at atomic resolution. My goal here is to summarize some of the most recent advances that have enhanced our prospects for understanding membrane proteins at the level of atomic structure.
