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Published on: November 5, 2019
An unusual cause of meningitis
Abstract:
A 57 year old man patient presented with fever and frontal headache. He had a background history of sero-positive rheumatoid arthritis which was well controlled on immunomodulatory disease modifying anti-rheumatoid drugs (DMARDS) including methotrexate and lef lunomide. Six months earlier he had returned from Massachussetts in the USA after a one year period of residence there. On examination his vital signs were within normal limits and he was afebrile with a temperature of 36.1oC. His left elbow joint was warm, tender and swollen; examination was otherwise normal.
Insights
A patient with rheumatoid arthritis developed fever and headache after returning from the USA. His swollen elbow indicated a potential infection or inflammatory flare.
Area of Science:
- Rheumatology
- Infectious Diseases
- Immunology
Background:
- A 57-year-old male with sero-positive rheumatoid arthritis, managed with disease-modifying anti-rheumatic drugs (DMARDs) like methotrexate and leflunomide.
- The patient had a recent travel history, residing in Massachusetts, USA for one year, returning six months prior to presentation.
Purpose of the Study:
- To investigate the cause of fever and frontal headache in an immunocompromised patient.
- To evaluate the differential diagnosis for a swollen, tender elbow in the context of rheumatoid arthritis and recent travel.
Main Methods:
- Clinical presentation review including patient history and physical examination findings.
- Assessment of vital signs and specific joint examination, focusing on the left elbow.
Main Results:
- Patient presented with fever and frontal headache, with a history of rheumatoid arthritis on immunosuppressive therapy.
- Physical examination revealed a warm, tender, and swollen left elbow joint; other findings were within normal limits.
Conclusions:
- The patient's symptoms suggest a possible infectious process or an inflammatory flare of rheumatoid arthritis.
- Further investigations are warranted to determine the etiology of the fever, headache, and elbow joint swelling.
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