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Updated: Jun 1, 2026

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
Published on: April 23, 2021
[Cognitive dysfunction in patients with subclinical hypothyroidism]
Robertta Soares Miranda Fernandes1, Nathália Bueno Alvarenga, Tamara Inácio da Silva
1Faculdade de Medicina, Instituto Metropolitano de Ensino Superior, Ipatinga, Brasil.
Objective:
Evaluate neuropsychological changes in patients with subclinical hypothyroidism (SH).
Subjects And Methods:
Cross-sectional study comparing the results of the neuropsychological evaluation of 89 SH patients and 178 individuals without thyroid disease. The participants underwent the following neuropsychological assessment: Conner's Continuous Performance Test (CPT-II), Iowa Gambling Task, Stroop Test, Wisconsin Card Sorting Test (WCST), Verbal Fluency Test (semantic and phonologic categories) and Rey Auditory Verbal Learning Test.
Results:
Among the neuropsychological tests, patients showed worse performance only in cognitive flexibility (WCST) and the ability to maintain sustained attention (omission errors on the CPT-II).
Conclusions:
These losses can cause detriments in the daily lives of patients, constituting potential treatment indications.
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